UK developer Positech Games current has a spaced based tower defense game in development. You'll be able to customize your fleet, give them orders, and send them into battle. While in battle you wont be able to give them orders, you'll just watch the battles play out much like tower defense game.
It should be released later this year.
Official Website
FAQ
http://www.youtube.com/watch?v=dfRXJFrPubs
It should be released later this year.
Official Website
FAQ
http://www.youtube.com/watch?v=dfRXJFrPubs